That is the thing. That folder, simply does not exist. It never existed. I am OCD with items on my computer. I am constantly monitoring & manually checking to see what is going on my computer & where. Not to mention all hidden files are set to viewable.
I boot up today & instantly get new alerts for my audio ( RtHDVCpl.exe ) & laptop touchpad ( SynTPEnh.exe ). Which both were previously marked as safe because I had to contend with alerts for them soon as I installed CIS. After setting these two items (again) to not run in sandbox & to trust the vendor for the files, I immediately reboot my pc. Upon Vista booting up, I again get the same alerts for the audio & touchpad as above, even though I chose to not run them in sandbox anymore & to make them safe files. Not to mention I am getting alerts for InputPersonalization.exe, which I also set to not run in sandbox again, & as a safe file.
Things I have placed as a My Own Safe File, simply don’t show up in the list for My Own Safe Files, or if one does show up in there, it vanishes at some point because it wont be there & I will get sandbox alerts for the program.
I have installed CIS close to 10 times trying to fix this problem. And now thanks to CIS not keeping safe files safe, with the advent of the alerts for SynTPEnh.exe, now my scrolling on my touch pad is disabled once again. 
And just now the blocked application of ask.com/updatetask.exe brings another alert. The file that doesn’t exist, is impervious to any of my CIS commands. I say block it & I still get alerts. This is driving me crazy.
Before using CIS, I had a mixed bag of my favorite security solutions installed ( like many people ). I was secure & satisfied to a point. The main problem was that all three running at once were a slight resource drain. I found CIS, & with it being all 3 of what I had in one application made me very happy. Low resource overhead & overall a superior product in all 3 areas (firewall/anti-virus/defense+) over what I have used in the past. I just have no idea why I am having these critical, yet simple errors.
I just got a google update alert since google was trying to make an outgoing connection. Just yesterday I set that same program alert for googleupdate, to allow it ( & remember my answer ). But apparently CIS isn’t remembering anything I tell, or at the least it in a random manner is choosing what to remember or what not to.
I am at my wits end because I have tried everything I can think of. The ghost ask.com folder/file can’t be helping things either. If CIS is going to bundle a malicious piece of junk like Ask.com, then it should at least be able to control, even when the user chose not to install Ask.com at all. ???
I hope someone can help, as I want to continue using CIS.