Yes, because it’s a failsafe if I do something wrong with CFW. It’s brilliant at blocking unsafe files and exploited lolbins etc.and I have a lifetime licence.
They work along side each other just fine though if I decide to run something in containment, Firefox for example, I get a CL exploit pop-up but it’s simple enough to allow but I’ve not had a in the wild example if it would show the same for a unknown file.
Anyway, they run fine together no issue really 
Total overkill as both default denying unknown files but in the case of CFW, it has to be vetted by Comodo before it’s allowed. Usual setup is CFW, CL and MD sometimes tweaked with DefenderUI though DUI not really needed.
