This is not a hack. Explorer.exe is also listed and was listed previously
comodo CIS C:\Windows\explorer.exe Access Memory … windows10 10.0.10532 - Comodo Internet Security - CIS / Install / Setup / Configuration Help - CIS - Comodo Forum
and here what is explorer.exe doing and why does DF+ block it in such high frequency? - Comodo Internet Security - CIS / Defense+ / Sandbox Help - CIS - Comodo Forum