Virtuemonde and Smithfraud help!!!

I am infected with Virtuemonde (Adware) and Smithfraud (Spyware), and I can’t rid myself of them! I have tried Spybot - Search and Destroy (which found them), said it removed them, but didn’t and Crawler’s Spyware Terminator. If anyone can offer assistance please help!

What I am running:

Windows Vista Home Premium 32bit
Comodo Internet Security
Avast! Professional Edition (with P2P shield, Web Shield, Internet Shield enabled)
Spybot - S&D
Spyware Terminator

Evening

Download Superantispyware ( http://downloads.superantispyware.com/downloads/SUPERAntiSpyware.exe )
update it
Boot in safe mode > Complete Scan

CG

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Xan