Unblock Applications

I have used Comodo security for years, and the latest edition has made it very hard unblock applications, files, folders, etc…
How to I unblock applications and not have them show in the block applications field?
How am I able to unblock and allow a folder and all files I save in that folder?
This makes no sense I have to constantly unblock every file I save or create in a folder.
The blocking delays my work way to much.
I am a software developer and I need to be able to use something like: \Folder\Application*