Remove the following (as always, let “hijack this” create a backup copy just in case)
(Remember after removing some of these in “R1” and “R0”, some might come right back. Don’t worry about it if it does) 
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = Bing
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = MSN
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = MSN
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = Bing
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = Bing
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = MSN
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
O1 - Hosts: ::1 localhost
O2 - BHO: (no name) - {5C255C8A-E604-49b4-9D64-90988571CECB} - (no file)
O4 - HKUS\S-1-5-19..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter (User ‘LOCAL SERVICE’)
After doing that, restart the computer. Then start the next section
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Do you use or require “Blue tooth” ??? (If your not sure, leave it alone)
If not, remove the following (as always, let “hijack this” create a backup copy just in case) 
C:\Program Files\WIDCOMM\Bluetooth Software\BTTray.exe
C:\Program Files\WIDCOMM\Bluetooth Software\BtStackServer.exe
O4 - Global Startup: Bluetooth.lnk = ?
O8 - Extra context menu item: Send image to &Bluetooth Device… - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie_ctx.htm
O8 - Extra context menu item: Send page to &Bluetooth Device… - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra button: [at]btrez.dll,-4015 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra ‘Tools’ menuitem: [at]btrez.dll,-12650 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
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If everything seems fine (Give it a few days just to be safe), I’d delete all the system restore points and create a fresh new restore point
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also
I would like to add that I have noticed my ram usage tends to be a bit higher than normal
While I never used skype, I'd check your skype options and make sure your not running "Supernode"
I checked process explorer and saw multiple rundll32.exe running.
Are they "signed" by mircosoft???
If not, upload it 1 by 1 of any unsigned rundl32.exe files to virustotal.com. <---Just optional, but feel free to double check if you like :)
Last, Are you running “magicjack” ??? I ask this because I saw it in your hijack this log