I have incorporated a number of entries to my hosts file, (C\Windows\System32\drivers\etc\hosts).
These all show quite happily in Online Armor’s, ( 
hosts section, so I am assuming they work OK.
Now, if I switch to Comodo V3, with Defence Plus enabled, am I likely to have conflicts because of these entries?
The only care Defense+ should have about your host file is when someone/something tries to modify it.