Comodo detecting latest version of Minitool Partition wizard as a virus.

Minti tool Partition Wizard notified me that there was an update. When I updated, however, Comodo notified me that there was a virus which it quarantined. Minitool finished installing but would not start up as it said there was a file missing. Is this a false positive or does Minitool actually contain a virus?

Most likely a false positive, but to be sure you should try to upload the file to virustotal to see if it gets picked up by any other vendor. Of course even if it does get detected, it can still mean its a false positive as you received the file through an internal program updater, so unlikely the update source is compromised.