Today about 20min ago I had to reboot my computer and found dat CIS 4 has made an update. Checking this my adjustments where gone. I set my virusscanner always to scan 1024mb and it was back to 20Mb. Maybe it did more but that I did not find now.
This means that this has happened to all my customers. Well back in the car and visiting a view hundred clienst 
UPDATE
Also my right mouse button is not working again…argggg