CIS v.12.0.0.6882 and above does not support Windows XP or Vista, period.
The containment and virtual desktop features haven’t worked on XP / Vista since CIS v.8.0 (2014). So even if you use an older CIS, you cannot take advantage of one of our strongest protection features.
Comodo strongly recommends anybody still using XP/Vista to upgrade immediately. Microsoft abandoned support for XP/Vista years ago, and the amount of serious vulnerabilities in these operating systems is almost innumerable. By using XP or Vista, you are exposing yourself to substantial risks which signature-based antivirus cannot protect you against.