Can a file be declared 'trusted' by automated (CIMA) analysis? [v5] [v6]

No it cannot.

Proving a file safe always involves manual checking by Comodo experts. Obviously automated checking may be involved as a first stage in such a process.

Comodo’s new service Valkyrie moves us closer to being able to verdict a file as safe, but even Valkyrie is only able to verdict the file as ‘highly likely’ to be safe.