My Defense+ Events log shows that it has blocked mscorsvw.exe from trying to modify a key and 2 files:
2014-03-03 18:58:15 C:\Windows\Microsoft.NET\Framework\v4.0.30319\mscorsvw.exe Modify Key HKLM\SYSTEM\ControlSet???\Services\clr_optimization_v4.0.30319_32
2014-03-03 18:58:15 C:\Windows\Microsoft.NET\Framework\v4.0.30319\mscorsvw.exe Modify File C:\Windows\Microsoft.NET\Framework\v4.0.30319\ngenofflinequeuelock.dat
2014-03-03 18:58:15 C:\Windows\Microsoft.NET\Framework64\v4.0.30319\mscorsvw.exe Modify File C:\Windows\Microsoft.NET\Framework64\v4.0.30319\ngenrootstorelock.dat
It repeats this about 40 times in a row within a minute. Is this malware?