Here is my set up which works great on both my pc’s with no slow downs at all.
Anti Virus = NOD32 3.0.667.0 w/ IE and FF under active mode for optimal web security
Firewall = Comodo 3.0.25.378
HIPS = Comodo 3.0.25.378
Virtualization = Sandboxie 3.26
On Demand Anti Spyware = SAS and MBAM
2Wire Gateway DSL Modem w/Hardware Firewall enabled on full stealth
Both my Desktop and Laptop have this same setup
AntiVirus: Avast 4.8 Home Edition
Firewall: CFP3
Anti Malware: BOClean 4.26 and a-squared anti malware
Edit: Haven’t had a virus for almost 7 months now :-TU
Got you beat Goose. No infections in over 5 years and I surf and download everything. A Squared always gave me false positives. It also says that GameSpy is spyware. Its the only program that ever does.
First PC - Main Dekstop
Kaspersky Internet Security 2009 and nothing more - no antispyware,virtualization or anything like that. If I’ll need them for a short time - I’ll download them ;D
Second PC - Test Laptop
Comodo Firewall v3 (Of course - always the latest version)
Comodo Memory Firewall v2 (Latest version too)
Comodo Vulnerability Analyzer BETA (If you count that as a security product - well it is ;D)
I never use mixed software, like antivirus this, antispyware that, firewall again from some different vendor. No, I never do that. EVER ! 
CFP3 w/Defense+
avast 4.8
(:HUG)
Current Running Processes
CFP 3 With Defense
Avira PE
BOClean
Comodo Memory Firewall
On-Demand
Superantispyware
Avast (Free)
CAVS 2
AVG Free
A-Squared Free
NOD32
Clam Win
Spyware Terminator
Other Related Security Apps
Comodo Back Up
CCleaner
JJS
Firewall: Comodo Firewall
HIPS: Defense+
Antivirus: None.
Antispyware: SAS.
Other: CCleaner
Josh
Prevention
Spybot - Search and Destroy’s immunize-function
Disabled useless, and potentially dangerous services
Harden-it
Secure-it
Real-time protection
Comodo Firewall Pro 3 with Defense+ in Paranoid Mode and the firewall in Custom Policy Mode
Comodo Memory Firewall
On-demand
Avira Premium (Avira Free when license expires)
Spybot - Search & Destroy
HijackThis
IceSword
ProcessExplorer
Other
Router with hardware firewall (MAC-filtering enabled, DHCP disabled, 30 character long WPA2-PSK-encrypted key, ping from WAN-side disabled, SPI enabled, UPnP disabled, DOS Protection enabled)
Firefox 3 with NoScript and Adblock Plus
All security patches from Microsoft
Running as Limited User
Some configuration with Group Policy Editor
Cheers,
Ragwing
I edit my post and added my hardware modem.
I also updated mine to include what security I use on my router.
My security realtime NOD32 CFP2.4 Boclean SB ST Cmf On demand S+D SAS MWB. Vettech mentioned his browser in active mode Nod32(advanced setting) what does this achieve plus other processes can have te same setting is it wise to check them all?
Open up NOD32 and click on the web browser section. Then click on the active mode. It enables extra filtering with no slow downs. You can test it out by going to the eicar site.
Hi guys
Firewall= Comodo with defense+ activated
Antivirus= none for now, waiting for CAVS3
On demand= MBAM
Surfing= Sandboxie, McAfee site advisor & Haute Secure
Cheers
Xman (:KWL)
Hey Xman do you have Sandboxie set up so the only thing that can run in the Sandbox is Firefox or IE? Very secure set up.
Hi Vettetech, IE running in Sandboxie :-TU
Xman (:KWL)
Hey Vettetech, restarted IE just now Sandboxed & noted that McAfee Site advisor is non-functional when running sandboxed but my trustworthy Haute Secure is running sandboxed though & all this with Comodo search as my homepage, I’m safe with Sandboxie & Haute Secure
Regards
Xman (:KWL)
This is my config file.
Under - [GlobalSettings]
ProcessGroup=<InternetAccess_DefaultBox>,iexplore.exe,firefox.exe
ProcessGroup=,iexplore.exe,sandboxiedcomlaunch.exe,sandboxierpcss.exe,start.exe,firefox.exe,PDFXCview.exe,
DivXsm.exe,mplayerc.exe,winamp.exe
Under - [DefaultBox]
ClosedFilePath=!<InternetAccess_DefaultBox>,\Device\RawIp
ClosedFilePath=!<InternetAccess_DefaultBox>,\Device\Ip*
ClosedFilePath=!<InternetAccess_DefaultBox>,\Device\Tcp*
ClosedFilePath=!<InternetAccess_DefaultBox>,\Device\Afd*
ClosedIpcPath=!,*
I’ve added the extra filtering to ie7 and opera should i enable it for the others like realplayer java comodo etc?
No if you read the instructions its only for web browser. Adding active mode for IE,FF and Opera is fine. Adding it for uTorrent and Limewire is good also.