I use the Cisco VPN (4.7). I have had no problems connecting to my primary site. I was surprised today when I tried to use the VPN to connect to a 2nd location and that connection repeatedly failed. I could connect when I shut down the firewall. I had no alerts and no log entries that showed blocked traffic.
Well with the Cisco VPN Client 4.8, the moment I connect to the VPN my Win 2k Machine reboots, the onlly way I can get it to work is to uninstall the Comodo Firewall