Hi, running W7Pro 64 bit with CIS 7 (4142 version) firewall and HIPs.
If I enable Viruscope, Windows Backup borks with ‘Access is Denied’ alert. Turning off Viruscope fixes issue. Can’t see an exclusion option? Any help gladly accepted. 
It seems like a bug which should be reported.
If you agree, you’ll find some good advice here: Comodo Forum