Update failed. Antivirus engine is not initialized

Core i7, 4 GB ram.
Windows 7 X64 russian
CIS 4.0.141842.828
Some time ago (couple of month, actually) windows start to complain that antivirus isn’t running. I ensured CIS is running and antivirus is switched on and forget about this. Now I’ve tried to perform full scan I’ve get “Update failed. Antivirus engine is not initialized” (by the way, russian translation of this message is awful).
Comodo internal diagnostic says all OK, process cmdagent.exe is running. What should I do?

Is the problem still happening?