System Information will not open

Comodo System cleaner works well except that System Information will not open.
Keep getting the annoying ‘Why not tell Mr Gates about it!’ Microsoft pop up.
Tried reinstalling (using Revo to uninstall, for good measure!) but it still happens with reinstalled programme.
Any ideas?

Currently using Online Armor firewall, Eset Nod 32 AV and Winpatrol free version