Spyware scan / Normal Scan ??

What does the spyware scan that the normal scan cant do? only scan the registry and the file system? different definitions?
If I want to check a computer I have to do both?

[i]NEW! Spyware Scanner and improved malware cleaning
CIS 5.x again fulfills the missing features of its predecessors by providing a new spyware scanner which is capable of scanning the windows registry and file system.

Note: We will be releasing the signatures for spyware scanning during the course of BETA testing. So you might not immeidately see this in action. i.e. next monday[/i]