I was uninstalling a ton of games/programs I no longer used. Afterwards I went to cleanup CIS and purged some of the entries in Firewall and Defense+, but when I was doing the Computer Security Policies it hanged for a little and then said that Comodo has crashed so I sent the crashlog to bugs email.
Not really sure way it crashed though, Win 7 SP-1, 4gigs, 2.90Ghz AMD Quad, CIS 5.10.228257.2253. I had that happen on a few other pcs n laptops but their specs are far lower