slowdown when using CIS 4 virtualization

I’ve noticed a noticeable slowdown in the system when using CIS 4 file and registry’s virtualization. Applications like auslogic registry cleaner or tune up utilities starts the registry scanning in more than 16 seconds. Strangely if I disable virtualization, leaving on sandbox, the same applications start in 7 seconds. ???
Also the time required for a complete scan is much higher.

+1

Yes. I’ve noticed that with regshot (registry snapshot utility).
4 sec. scanning entire registry without virtualization active versus 28 sec. with virtualization
Moreover I have noticed a little slowdown on many applications I think in relation with slowed registry access