Security alerts

So what should I do to stop the alerts coming up and are they safe?

Please could someone suggest what to do. I am browsing and these alerts just keep coming. Should I allow them or not? If I deny them I can’t browse any more. What are they coming up for when I have IE on the allow application list. I really dont understand at all.

Thank you very much. :SMLR

You have to allow it or you wont be able to surf OLE Auto is part of Microsoft & internet explore.exe is the main part of explorer