Safe program mistakenly isolated

While running a recently d/loaded program (GMER rootkit detector) I inadvertently selected Treat application as an ‘Isolated application’ after an alert appeared. (I think it was a registry alert)
Now I cannot start the program and get a pop up message to the affect of ‘cannot find path or no permission’.
Is there some way I can ‘un-isolate’ this file? I’ve looked through various settings but can’t find anything. :frowning:

EDIT: Renamed the file concerned and rebooted and it now runs ok (with appropriate alerts checked)
Don’t know whether it was the renaming or rebooting or both that did it!

It’s in the FAQ’s here: