My Pending Files Query?

I keep the files registered in My Pending Files tidy on a daily basis by first purging and then adding to my safe list the ones the remaining ones I know to be ok, then sending the remainder to Comodo.However every day when I sign into my PC I have the same two entries. One is the daily update for my Avira Antivirus which I understand will be an altered file if it has just updated and therefore Comodo will query it.

the one I don’t understand though is the one written like this.
C:\ Documents and settings\Local Service\Application Data\Microsoft\UPnPDevice Host\upnphost\udhisapi.

As far as I know I think this is a safe process but not entirely sure. Is there a rule I need to set for this application?.