MSIE 8.0 and protected mode

I have a Citrix app which will run under MSIE 8.0 only if protected mode is turned off. Does the Comodo HIPS (or another module) protect well enough to be confident running it that way?

Welcome to the Forum, bobhock
Yes, Defense+ will protect you from anything unwanted running without your permission

defense + is just defense + extra defense … (:WIN)