MSE conflicts with Defense+?

Good morning,
I recently installed “Comodo Firewall”. It is included in the Defense + feature, but having already installed on your computer “Microsoft Security Essential,” I wanted to know if Defense+ conflicts (sooner or later) with MSE. If so, how would you advise me to do?

I await your kind response soon.

MSE is not a known problem maker. From what I have seen the two of them work together nicely.

Ok, thanks.
Good New Year.