Monitoring of programs installed prior to COMODO installation

I have been told that CIS does not monitor the activity of programs installed before Comodo.
Could I get some clarification on that?
Obviously, CIS will alert for unrecognized files when they execute.
So what does it NOT monitor?

HIPS will always monitor because it is based on a combination of rules and file rating (assuming safe mode is used). Auto-containment is based on rules so if you’re using the default internet security config which is set after installing both the AV and firewall, then previously installed unknowns will not be auto-contained because they won’t match the default auto-containment rules. Firewall is based on rating and rules, VirusScope recognizer work on only those rated as unrecognized, and by default (IS config) only unrecognized running in containment.