Light System Virtulization - Exclusion lists

Hey guys, As we all know vitrualization has been very effective vs malware but when you have a file, or folder excluded… how will everything turn out then? Sure, It will keep your files safe that aren’t excluded, but what about those files that are excluded?

Example; If I have my system in virtulized and I then exclude folders like “Downloads” Game folders, Certain App data folders (Such as Opera Data so it will remember my preferences)

All those files and folders are now open for modification, Whether it be a patching virus such as virut or something else.

What do you think?