Is there a way to configure Comodo sandbox so, that it automatically sandboxed only removable drives like cd/dvd and usb flash and not other programs?
You can set exclusions for autosandbox under defense+ settings, behaviour control.
But i dont know if it automatically works with cd etc then.
If you depend on the autosandbox, the exclusion can be translated as a hole in security. So to say.
Files on removable media are by default untrusted; its just the nature of the beast.
Sandboxing occurs resultant to recognition.
Here are the pertinent rules for the sandboxing game:
Well I wanted that autosandbox occurred despite of there is good files or bad ones for removable drives, but it appears that it isn’t working this way, would be nice if comodo added this feature to their sandbox 
thanks for your replies.