Internet Explorer

I’m not sure what’s going on, but I cannot open internet explorer. I feel that it has something to do with Comodo, and possibly the sandbox, but I can be sure. This also happened with Firefox (I switched to Google Chrome after that), but I still need IE for some web pages.

Can anyone help me out with this?

To see if it related to CIS please take a look and post a screenshot of the D+ logs. They are under View Defense + Events.

Also test your system for malware with the following scanners:
Hitman Pro
Malwarebytes Anti Malware Free edition
Super Antispwyare Free edition

An idea,
If it happens with IE and Firefox, try this

While browser add-ons can enhance your online experience, they can occasionally interfere or conflict with other software on your computer. Try starting Internet Explorer without add-ons to see if the problem goes away. Here's how:
Click the Start button Picture of the Start button, click All Programs, click Accessories, click System Tools, and then click Internet Explorer (No Add-ons).

If disabling all add-ons solves the problem, you might want to disable all add-ons and then turn on add-ons only as you need them. This will allow you to figure out which add-on is causing the problem