How to prevent any programs from being installed from a CD?

What is the best way?
thanks in advance,

BK WI

This have nothing to do with Comodo. Simple disable auto runs. TweakUI can help you there.

It can be done but take care not to block too much or your computer will not work. Select the group for all applications in defence+, computer security policy. Go in to access rights. Against run an executable select modify. In the blocked applications list add E:* or whatever drive letter is your CD drive. This will stop any programs from the CD and not just installations.