How to Block special DLL file,Don't kown the path

How to Block special DLL file,Don’t kown the path,

like “usp10.dll”;

You can use wildcard characters in CIS. So, adding a blocked file (Add - Browse…) of “*\usp10.dll” (without the quotes) should do what you need. I say should, since other than specifying a drive (eg. C:*\file.exe) I’ve not actually tested this myself.