If the user knows that the application in question is safe or can be trusted, then they can manually define such rating in the local file list database. Otherwise do nothing and only remove the entry from the database if the application no longer exists on the system, as the entry will be re-added when the unknown program is executed again.
I do not know how they handle them. There are thousands of files rated “Unknown” into cloud.
1 year-2years passed but they are still “Unknown”
Other vendors are better or best on their cloud systems. They handle the all files in 2 days.
Is it malicious or not?