How do i exclude a folder to be monitored by Defence+ ?

How I can exclude a folder from Defence+ ?  ??? ???
The problem is that there is a certain application I use and it will keep on changing the application and run it. But every time the compilation is done and run, Defence+ will pop up and tell that it has being isolated.  :-TD
I want to exclude that particular folder from being monitored! How do I do that?