file or directory corrupted and unreadable

I get error messages on the log stating certain mp3’s werent transferred. They had been one time, but on the second backup, the messages appeared. When I go to the “E” drive and click on the files, it says that it is not accessable, that the file is corrupted and unreadable. I can access them on the “C” drive with no problem. I cannot delete or do anything with them on the “E” drive. Any thoughts or solutions? Thank you.