Exclude a registry key from being protected

Hello. I need to run a program, but after installing the AV (alone) the program says it has not access to the registry key, because the access is prohibited. How can I exclude this registry key from being protected, or another suggestion?
Vista 64 bit and this is they key I want to unprotect
HKEY_USERS\S-1-5-21-2375458763-3175993-1728609748-1000\Software\Classes\Wow6432Node\CLSID{98110160-BE78-5988-6390-CBC86CAE0C93}\Implemented Categories{CCBAE3C7-31D8-D3BA-EAB6-F69921043E18}
Thank you for any support