Does the AV scan the registry?

Cause I noticed on 1 of the pcs I have ran a full scan with the latest definitions from Comodo, and it detected C:\Windows\System32\Socks.exe, not 100% when or how it got in there but idk if it spreads to the registry or not. Does the AV scan registry on Full Scan or is there an option to scan the registry? Just wondering

Thanks Kefka