Comodo should be able to automatically detect if there is a Full Screen Application running (ie. a game) and temporarily disable updates until that application is closed. This will prevent lag during games while the database is being updated. Many AVs have this option and I believe that CIS should also.
Sorry, I did not notice that this topic has already been addressed. Here is the link for that discussion.
https://forums.comodo.com/anti_virus_wishlist/silent_updates-t30414.0.html