Defense+ slow to respond - apps hang, pop-ups slow to show

Defense+ is getting on my nerves. It is slowing down my productivity on my computer.
For example: When I try to install a new application, the installer will hang for about 10-30 seconds, and then finally Comodo pops up a Defense+ message to allow/deny this operation. Even if I put Comodo in INSTALL mode, certain applications take a long time to install. This behavior also occurs, even when I’m running programs and Comodo finds something new about the program. So it doesn’t only occur during new installs!

I don’t understand why Comodo takes so long to respond back to the application to allow it to do it’s thing, and show me a pop-up?

This is unacceptable behavior.

Do you have any other security software that could possibly conflict with Defense+?