Defense+ conflict with Vista UAC?

I run Dreamweaver MX 2004 under Vista Home Premium (32 bit) UAC and it will only run when Defense+ is disabled. Under any other Defense+ setting, having gone through the usual UAC rigmarole, I get the standard Windows “Dreamweaver MX 2004 has stopped working” message.

Dreamweaver is the only programme that I run under UAC and the only program that gives me this problem - is there some sort of conflict between CIS and Vista UAC or am I adding 2 and 2 together and making 5?

I do not wish to disable Defense+ (as I have been doing for some time now) and would really like some insight as to both the cause and the resolution to this problem.

Many thanks in anticipation.