Defense+ Causing "Server Execution Failed" When Protecting COM+ Interfaces

OS: Windows 7 Ultimate RC Build 7100
CIS Version: 3.14.130099.587

When Defense+ is active (I use paranoid mode), a lot of Windows executables (most notably explorer) will give an error saying “server execution failed” due to protected COM+ interfaces. Defense+ does not ask to allow / block anything.

The following Microsoft KB article may be relevant: