Compatible with Avast?

Hi. I have avast 4.8 home antivirus on my computer with vista os. Is comodo compatible? Do I need both, etc.? Thanks

if you plan to keep avast, then you should disable the AV module of CIS or keep CIS AV, but use avast as on demand scanner only. shouldn’t have 2 active/realtime AVs on 1 computer.
it’s like 1 guy having 2 girlfriends … 88)
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2 girlfriends?
http://i40.tinypic.com/34rvuo6.gif

thanks