Comodo Internet Security + Malwarebytes PRO

Viable strategy or shouldn’t run those 2 programs at once ?

only if you run comodo firewall + defense +. if you want to run malwarebytes pro you cant run comodo antivirus. you cant run 2 realtime antivirus scanners at once

Turn off real-time Comodo AV module and use it as on-demand scanner.

Malwarebytes Pro is one of the best virus scanners. It can detect almost everything.

There is a compatibility issue when using Malwarebytes pro real-time and CIS real-time scanners at the same time. See this post:

https://forums.comodo.com/install-setup-configuration-help-cis/cis-and-malwarebytes-pro-t74278.0.html;msg529707#msg529707