There are a lot of discussion about cloud scanning.
Immunet and Panda were the popular first ones.
There is another player in the game. Comodo version 5
The advantage of having a good protection (or, in my case a good second opinion on-line but not resident).
But keygen are not always malware. May be this detection is not really malicious but the detection is coz its keygen. I read in False postive thread here, regarding a keygen detection by CAV, one of the Devs mentioned that keygen are not always malicious so if you trust it you should exclude it from CAV’s detection. So i guess Avast didn’t missed this detection miserably.