Comodo Anti-Virus and Avast Question

I have Avast installed and running, however, I also would like to install and run the Comodo anti-virus.
Is this possible?would there be any bad effects on my computer/programs?

Thanks

You should never have more than one active antivirus application on your system. You can disable the real-time functionality of the AV in CIS and use it for on-demand scans though. Just disable the real-time functionality of Avast when you run the on-demand scan.