Have you ever heard of Bromium vSentry. Its goal is to protect users with micro hardware based VMs.
http://www.networkworld.com/news/2012/091912-bromium-262567.html?page=1
http://www.esecurityplanet.com/news/bromium-vsentry-defends-enterprises-with-microkernel-virtualization.html
http://www.bromium.com/news/bromium-introduces-vsentry-first-product-protect-enterprise-design.html
What do you think of it. Could it be more efficient than Sandboxie or CIS Sandbox?