Anti-virus scan, including program links

Maybe I am in the wrong forum, please direct me to the more suitable.
For example, after installing some free software, you can easy get this situation - you have cleared register and files, but EVERY time you open browser, you have new tab with specific web-page opened.
The reason is simple:
program link is this like

"C:\Program Files\Internet Explorer\iexplore.exe"

So, it is very nasty, and also very easy to detect and not a problem to solve.

In other words, you would like to repair such a scenario : where unwanted applications change your homepage. Not sure about detection, especially from the Antivirus module.
Normally, unwanted application should get sandboxed while preventing homepage modifications.

More over, properly configured HIPS should handle the job. Theoretically, KillSwitch should be helpful if you are considering"Quick Repair…" actions from “Tools” tab.

Hope it helps.