Almost every program tries to access the memory of others?

Every now and then, if I have the Paranoid Mode or Safe Mode enabled in Defense+, I start getting alerts about nearly every running program trying to access the memory of most of the other running programs (excluding atleast windows system programs). I’m not sure what Comodo is catching there, but if I have the Training Mode enabled, no interprocess memory access rules get written.

Has anyone else experienced the same problem? Just want to ask this before I start to test further with clean reinstalls and rules from scratch…

Comodo Firewall Pro 3.5.54375.427
Windows XP Professional SP3
Other security products: Avira AntiVir Personal Edition