i have the new version “COMODO Internet Security 5.9.219747.2195”.
i installed it today, 12-20-11, did you by chance disable the manual updates ?, i tested that part out and it pops up saying “The system cannot find the file specified”
funny how this bug pops up after i updated today, so is that part disabled on this site ?.
here is a link(kinda old), so this has happened before.