Thanks for your suggestion.
Meanwhile as another test, I imported a fresh default Firewall Security configuration file (taken from C:\Program Files\COMODO\COMODO Internet Security directory) into CIS than restarted the system and did wait a little for the Home Network Zones to be created (playing around with some apps to trigger network connections).
Now the same issue happens again, again a NON local IPv6 address is listed in Home #1 next to a local IPv4 192.168.xxx.xxx address.
Of course one can work around this issue but key point here is that CIS, with a default config, assign a NON local IPv6 address automatically to a Home Network Zone which it should not do because it causes security issues.
EDIT: Oh I forgot to mention, with the default config the "Filter IPv6 traffic" setting is disabled and yet a IPv6 address is added to a Home Network Zone?

BUG !