AFAIK, CIMA will act as another form of heuristic with behavior blocker in CIS v4; So you will have AV Heuristics and Behavior Blocker + CIMA working together on that side. Not 100% sure, Hopefully Melih can explain a bit more.
I’d supposed that, in the CIS CIMA module, Comodo would put algorithms that take too long to be executed in real time or during a comprehensive scan.
So maybe CIS will put up an alert re some suspect behavoir, and offer the opportunity to perform further more thorough analysis (& give technical feedback) to inform your allow/not decision. In this way CIMA would enter the decision-making process at much the same point as either 1) Threatcast and/or 2) “my pending files” examination. I guess if it enters at the threatcast point, it would improve the quality of threatcast scores. (Threatcast could even weight more highly allow/deny decisions made by people who had run CIMA on a file).